ADMET and DMPK, Vol. 4 No. 3, 2016.

Table of contents

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ADME/DMPK in the development and use of tyrosine and serine-threonine kinase inhibitors (page 182-185)

Godefridus Peters, Kin Tam
Editorial

Tyrosine kinase inhibitors for EGFR- and ALK-mutated non-small cell lung cancer (page 186-211)

Jonathan R. Thompson, Smitha P. Menon, Grace K. Dy
Review article

Cardiovascular safety of protein kinase inhibitors: putting their “QT-phobia” in perspective (page 212-231)

Rashmi Shah
Review article

Cross talk of c-Jun N-terminal kinase and p38 map kinase modulate insulin and TNFα-stimulated VCAM-1 expression in rat aorta endothelial cells (page 232-240)

Gregory B. Pott, Mark Tsurudome, Jamie Bui, Chelsea Gardner, Marc Goalstone
Original scientific paper

Dose optimization of ceftriaxone-vancomycin combination using fractional inhibitory concentration kinetics in resistant bacteria (page 241-260)

Vishnu D Sharma, Aman Singla, Manu Chaudhary, Mukesh Kumar, Anuj Bhatnagar, Shailesh Kumar, Manish Taneja
Original scientific paper

Evaluation of P-glycoprotein expression in pain relevant tissues: understanding translation of efflux from preclinical species to human (page 261-268)

Renu Singh Dhanikula, Cyrla Hoffert, Rebecca Grant, Denis Projean, Rosemarie Panetta, Dajan O’Donnell, Marie Roumi
Original scientific paper

Evaluation of pharmacokinetic and pharmacodynamic interaction between repaglinide and atazanavir in healthy, diabetic and hepatic impaired rats: possible inhibition of CYP3A, OATP, and P-glycoprotein transporters (page 269-279)

Thirumaleswara Goud, Srinivas Maddi, Nayakanti Devanna, Thatipamula Rajendra Prasad
Original scientific paper

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