Meeting abstract
Application of Tricalcium Phosphate in the Treatment of Large Bone Cavities of Jaws
Goran Knežević
Abstract
Tricalcium phosphate - Ca3(PO)2 is a resorptive and bio-compatible calcium phosphate ceramic with the ratio of calcium and phosphate atoms very similar to natural osseous mineral. Thus in the tissue it behaves like its own bone transplant. On the market it appears in the form of granules of different size. It gradually becomes entirely resorbed during the conversion of bone and substitution with new osseous tissue. In oral surgery it is mainly applied for major bone defects which occur after cysts and tumours operations, and in dental implantology. It can serve as a carrier of osteoinductive supplements, such as morphogenetic protein, and maintain its activity. The best known representatives of this group are Ceros 82, Calciresorb, Sinthograft, Augmen, Ilmaplant, while more recent are Cerasorb, Bio-Resorb and Biovision, preparations on the basis of beta-tricalcic phosphate.
The purpose of the paper is to show the dynamism of healing bone defects of the jaw, remaining after operations for cysts, tumours, or other pathological lesions, which are filled with granulate Bio Resorba, and to compare them with other wellknown methods of treatment.
The procedure was carried out in hospitalised patients with their consent in the Clinical Department of Oral Surgery, University Hospital “Dubrava.” The bone defects were filled with the appropriate amount of granulates, 1 000 -2 000 μm in size. Healing results were subjectively evaluated by analysis of radiographs after 2, 4, and 6 months and compared with the healing of the same kind of cavities treated by other procedures.
Out of 37 cases Bio-Resorb was applied in 10 cases (3 radicular cysts, 2 follicular cysts, 2 odontogenic keratocysts and three traumatic bone cavities/cysts), which resulted in bone cavities larger than 3 cm in diameter. In one case a female patient developed infection and rejection of the granules, and repeated inflammatory problems lasted for two months after the intervention. No other patient showed complications, and the renewal of bone structure was completed in the period from 4 to 6 months after the intervention. The presented examples and their comparison with the results obtained by methods of excochleation and decortication of the jaw, or excochleation and permanent post operational suction, favour the application of resorptive tricalcic phosphate, particularly in the treatment of large traumatic bone cavities. This method ensures faster establishment of the expected bone structure than other applied methods.
Keywords
Hrčak ID:
608
URI
Publication date:
15.12.2005.
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