Professional paper
The effects of Ibuprofen-releasing foam dressing on wound pain in leg ulcers
Maja Lenković
; Department of Dermatovenereology, Clinical Hospital Center Rijeka, Rijeka
Zrinka Stanić Žgombić
; Department of Dermatovenereology, Clinical Hospital Center Rijeka, Rijeka
Teo Manestar-Blažić
; Department of Dermatovenereology, Clinical Hospital Center Rijeka, Rijeka
Ines Brajac
; Department of Dermatovenereology, Clinical Hospital Center Rijeka, Rijeka
Leo Čabrijan
; Department of Dermatovenereology, Clinical Hospital Center Rijeka, Rijeka
Abstract
Aim: Ulcus cruris represents one end-point of complications linked to the venous hypertension of lower extremities, as inadequately supplied sclerotic tissue breaks down and healing is largely impaired. Today the advanced leg ulcer treatment is based on wound dressing that can contain analgesics in order to diminish pain. The aim of this non randomized one year study was to analyze the effects of ibuprofen-releasing foam dressing on wound pain in leg ulcers in order to ameliorate the quality of life in patients. Methods: In this one-year study 288 patients with leg ulcers were analyzed, among which 28 patients were prescribed ibuprofen-releasing foam dressing without peroral analgesic therapy, while 30 patients continued peroral analgesic therapy with silver-releasing foam dressing as a control group. The primary endpoint was to determine wound pain relief in the first two days among patients treated with. Results: We observed a statistically significant decrease of pain intensity in the first two days of therapy, but not a significant different rate of ulcer healing compared to the control group. Conclusion: Based on these results we concluded that foams with analgesics could be a treatment of choice for chronic leg wounds with intense pain.
Keywords
ibuprofen-releasing foam; leg ulcer; wound pain
Hrčak ID:
84198
URI
Publication date:
4.6.2012.
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