Review article

MALIGNANT DISEASE IN POTENTIAL RENAL TRANSPLANT RECIPIENTS – DIAGNOSTIC AND THERAPEUTIC CHALENGE

DUBRAVKA MIHALJEVIĆ ; Osijek University Hospital Center, Department for Dialysis, University Department of Medicine, Osijek and Zagreb University Hospital Center, Croatia
NIKOLINA BAŠIĆ-JUKIĆ ; Zagreb University Hospital Center, Department of Nephrology, Arterial Hypertension and Dialysis, Zagreb, Croatia
MARKO JAKIĆ ; Osijek University Hospital Center, Department for Dialysis, University Department of Medicine, Osijek and Zagreb University Hospital Center, Croatia

Abstract

Renal transplantation is the treatment of choice for many patients with end-stage renal disease. There are a few generally accepted contraindications to transplantation: active infection, malignancy, substance abuse or non-adherence to therapy, chronic illness with life expectancy of less than one year, and poorly controlled psychosis. Potential renal transplant candidates must undergo thorough screening for exclusion of malignant diseases, with an individual approach to each patient. Patients with a history of malignancy might be placed on the waiting list for renal transplantation after a waiting period, which depends on the type of tumor and individual patient characteristics, and there are no signs of tumor. This group of patients require careful surveillance during the waiting time, as well as after transplantation.

Keywords

malignancies/cancer; dialysis; end-stage renal disease; renal transplantation; waiting list; imunosuppresive therapy; cytotoxic drugs

Hrčak ID:

89623

URI

https://hrcak.srce.hr/89623

Publication date:

1.3.2011.

Article data in other languages: croatian

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