Review article
Silent brain infarct
Lidija Tuškan-Mohar
; Klinika za neurologiju, KBC Rijeka, Rijeka
Adriana Prunk Drmić
; Klinika za neurologiju, KBC Rijeka, Rijeka
David Bonifačić
; Klinika za neurologiju, KBC Rijeka, Rijeka
Igor Antončić
; Klinika za neurologiju, KBC Rijeka, Rijeka
Olivio Perković
; Klinika za neurologiju, KBC Rijeka, Rijeka
Siniša Dunatov
; Klinika za neurologiju, KBC Rijeka, Rijeka
Abstract
With its onset and symptoms the acute brain stroke causes relatively clear and recognizable
clinical features. However, there are chronic, single and/or diffuse ischemic brain lesions
which are clinically asymptomatic and which take longer to recognize. The term ”silent
brain infarct” is frequently used to describe the brain infarct which is determined with the autopsy
by chance or which could be determined with computerized tomography. Such brain infarct
could also be determined using the brain magnetic resonance imaging on people who
never before had clinical symptoms transient ischemic attack or brain stroke in their lives. For
the most of the time this is about small infarct in deep sub-cortical brain regions. It is morphologically
similar to symptomatic lacunar infarct. Lacunar ischemic brain lesion is the consequence
of the deep, perforating artery occlusion. Its base is mainly the hypertensive brain
microangiopathy. The silent brain infarct is given great attention in the last decade because
the studies show the silent brain infarct presence doubles the symptomatic brain stroke and
dementia risk. In this review we show the epidemiology, the pathophysiologic attributes, the
risk factors and possible silent brain infarct consequences.
Keywords
cerebral microangiopathy; dementia; risk factors; stroke
Hrčak ID:
98606
URI
Publication date:
4.3.2013.
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