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ROLE OF NEGATIVE PRESSURE THERAPY IN THE TREATMENT OF CHRONIC WOUNDS

DUBRAVKO HULJEV ; Center for Cosmetic and reconstructive Surgery, university Department of Surgery, Sveti Duh university Hospital, Zagreb, Croatia
ALEKSANDAR GAJIĆ ; Dr. Miroslav Zotović institute of Physical Medicine and rehabilitation, Center for Hyperbaric Medicine and treatment of Chronic Wounds, Banjaluka, Bosnia and Herzegovina
TUGOMIR GVERIĆ ; Center for Plastic and reconstructive Surgery, university Department of Surgery, Sveti Duh university Hospital, Zagreb, Croatia
NADA KECELJ LESKOVEC ; University Department of Dermatovenereology, Ljubljana, Slovenia
CIRIL TRILLER ; University Department of Surgery, Division of Surgical infections, Ljubljana University Hospital Center, Ljubljana, Slovenia

Abstract

Negative Pressure Wound Therapy (NPWT) is one of the supportive options for chronic wound treatment. The level of negative pressure is between 40 and 125 mm Hg below ambient. Good results in increasing angiogenesis, improvement of blood flow in wounds, edema reduction, regulation of moist environment, granulation tissue stimulation and wound retraction have been proved. In addition, bacterial burden in the wound and the amount of harmful products (exotoxins, endotoxins, cytokines and matrix metalloproteinases) are also significantly reduced. Chronic wound healing time is accelerated in comparison with other conservative treatments. The NPWT can be applied in either inpatient or outpatient settings.

Keywords

negative Pressure Wound therapy (nPWt); chronic wounds

Hrčak ID:

98641

URI

https://hrcak.srce.hr/98641

Publication date:

25.2.2013.

Article data in other languages: croatian

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