Professional paper
https://doi.org/10.2478/10004-1254-64-2012-2275
Severe Renal Function Impairment in Adult Patients Acutely Poisoned with Concentrated Acetic Acid
Andon Chibishev
; University Clinic of Toxicology, Skopje, Republic of Macedonia
Aleksandar Sikole
; University Clinic of Nephrology, Skopje, Republic of Macedonia
Zanina Pereska
; University Clinic of Toxicology, Skopje, Republic of Macedonia
Vesna Chibisheva
; Clinical Center Skopje, University “Ss Cyril and Metodius”, Medical faculty, Skopje, Republic of Macedonia
Natasha Simonovska
; University Clinic of Toxicology, Skopje, Republic of Macedonia
Nikola Orovchanec
; Institute for Epidemiology, Biostatistics and Medical Informatics, Medical faculty, Skopje, Republic of Macedonia
Abstract
Acetic acid is a widely used organic acid with corrosive properties that depend on its concentration. If acetic acid is ingested in concentrations above 30 % it may severely damage the upper gastrointestinal tract and cause intravascular haemolysis, which can result in severe kidney and liver disorders and disseminated intravascular coagulation. In this retrospective study, we analysed acetic acid ingestion data collected at the University Clinic for Toxicology of Skopje, Macedonia from 1 January 2002 to 31 December 2011. The analysis included systemic complications, kidney damage, and the outcomes in particular. Over the ten years, 84 patients were reported at the Clinic to have ingested highly concentrated acetic acid. Twenty-eight developed kidney disorders, while the remaining 56 had no complications. Fatal outcome was reported for 11 patients, seven of whom had systemic complications and four severe gastrointestinal complications.
Keywords
corrosive poisonings; esophagogastroduodenoscopy; post-corrosive stenosis; renal failure
Hrčak ID:
98697
URI
Publication date:
20.3.2013.
Visits: 3.298 *