Original scientific paper
Developmental Anomalies of Genetically Instable Teeth
Asja Miličić
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Vesna Gaži-Čoklica
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Marina Lapter
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Abstract
Aplasia, a rudiment-shaped crown and delayed development of dental germs of genetically instable teeth are biologically dependent phenomena caused by the same gene with pleiotropic manifestations.
The aim of the study was to assess the presence of these three forms of genetic instability, by the analysis of 10,140 orthopantomograms of orthodontic patients. A sample of 973 patients with a finding of aplasia, rudimentary forms or delayed development of one ore more teeth, with the exception of third permanent molar, were singled out.
Individual presence of each anomaly, distribution of the findings according to type and number of affected teeth, and the frequency of concurrent presence of two or all the three anomalies were determined in the selected sample, revealing the following: — in the total sample, the percentages of aplasia, rudimentary forms and delayed development were 7.99%, 2.6% and 1.09%, respectively;
— 1530 teeth were missing due to aplasia, there were 306 rudimentary forms, whereas developmental delay was recorded in 134 teeth;— in the selected sample, aplasia was most frequently found as a solitary anomaly (83.25%), whereas rudimentary forms (25.18%) and delayed development (11.41%) were significantly more commonly observed in combination with another anomaly; — most patients had two (44.69%) or one tooth (39.75%) missing, whereas the anomalies of rudimentary form and delayed development most frequently involved one tooth only (75.10% and 81.08%, respectively); — upper lateral incisor was most frequently missing (41.50%), followed by lower second premolar (34.12%), second upper premolar (18.69%) and lower central incisor (4.97%);
— upper lateral incisor was most frequently affected by the rudimentary form anomaly (97.39%), whereas these forms were
quite infrequently recorded in lower second premolar (0.65%);molar (41.04%), followed by upper lateral incisor (32.09%) and second lower premolar (26.87%); and — aplasia and rudimentary forms were found to most frequently occur in combination (62.17%), followed by the concurrent presence of aplasia and developmental delay (23.24%) and rudimentary tooth and developmental delay (10.27%), whereas a combination of all the three anomalies was most infrequently observed (4.32%).
Keywords
genetically instable teeth; aplasia; rudimentary teeth; delayed development of tooth germs
Hrčak ID:
99422
URI
Publication date:
15.12.1994.
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