Original scientific paper

THE PREVALENCE OF CARDIOMETABOLIC RISK FACTORS AND THE TEN-YEAR RISK OF FATAL CARDIOVASCULAR EVENTS IN PATIENTS WITH SCHIZOPHRENIA AND RELATED PSYCHOTIC DISORDERS

Dita Protopopova ; Department of Psychiatry, Medical faculty, Charles University and University Hospital, Hradec Kralove, Czech Republic
Jiri Masopust ; Department of Psychiatry, Medical faculty, Charles University and University Hospital, Hradec Kralove, Czech Republic
Radovan Maly ; Department of Internal medicine, Medical faculty, Charles University and University Hospital, Hradec Kralove, Czech Republic
Martin Valis ; Emergency Department, University Hospital, Hradec Kralove, Czech Republic
Jan Bazant ; Department of Psychiatry, Medical faculty, Charles University and University Hospital, Hradec Kralove, Czech Republic

Abstract

Background: People suffering from schizophrenia have a significantly shorter lifespan compared to the general population. The
majority of deaths are caused by physical diseases, including cardiovascular events. The aim of this cross-sectional study was to
predict the risk of premature cardiovascular mortality and assess the prevalence of cardiometabolic risk factors in a sample of Czech
patients with schizophrenia and related psychoses.
Subjects and methods: We reviewed data from 129 subjects treated in an outpatient clinic that specialised in psychoses. The
main collected variables included basic physical parameters (height, weight, waist circumference, blood pressure), smoking habits,
laboratory data (glucose level, serum lipid level) and an electrocardiograph (ECG). We calculated the ten-year risk of fatal
cardiovascular events using the Systematic Coronary Risk Evaluation (SCORE) chart.
Results: The most prevalent risk factors were being overweight (70% of patients had a BMI over 25), dyslipidaemia (70% of
patients) and smoking (43% of patients). According to the SCORE diagram, there was a high risk of fatal cardiovascular events over
a ten-year period in 10% of the study group. The percentage was even higher (24%) when the latest European guidelines for
cardiovascular disease prevention were used to calculate the risk.
Conclusions: Our outcomes indicate even higher cardiometabolic morbidity rates in patients with psychoses than those
referenced in the literature.

Keywords

schizophrenia; cardiovascular; risk factor; mortality

Hrčak ID:

106240

URI

https://hrcak.srce.hr/106240

Publication date:

24.9.2012.

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