Medicina Fluminensis, Vol. 50 No. 1, 2014.
Review article
Metabolic complications after solid-organ transplantation
Ivana Mikolašević
; Zavod za nefrologiju i dijalizu, Klinika za internu medicinu, KBC Rijeka, Rijeka
Vesna Lukenda
; Klinika za internu medicinu, OB „Josip Benčević“, Slavonski Brod
Branka Sladoje-Martinović
; Zavod za nefrologiju i dijalizu, Klinika za internu medicinu, KBC Rijeka, Rijeka
Luka Zaputović
; Zavod za kardiologiju, Klinika za internu medicinu, KBC Rijeka, Rijeka
Ljiljana Bulat-Kardum
; Zavod za pulmologiju, Klinika za internu medicinu, KBC Rijeka, Rijeka
Davor Štimac
; Zavod za gastroenterologiju, Klinika za internu medicinu, KBC Rijeka, Rijeka
Sanjin Rački
; Zavod za nefrologiju i dijalizu, Klinika za internu medicinu, KBC Rijeka, Rijeka
Lidija Orlić
; Zavod za nefrologiju i dijalizu, Klinika za internu medicinu, KBC Rijeka, Rijeka
Abstract
Solid-organ transplantation is the optimal method of treatment in patients with end-stage renal, heart and lung disease, as well as those with end-stage liver disease (acute or chronic). Advancements in immunosuppressive treatment of solid-organ transplant recipients significantly increased graft and patient survival and significantly lowered the incidence of rejection crises. Efforts to increase long term patient and graft survival are directed to the prevention and treatment of cardiovascular diseases, because they are the leading cause of mortality in these patients. Traditional risk factors for the development of cardiovascular diseases (e.g. arterial hypertension, post-transplant diabetes mellitus and metabolic lipid disorder) are more common among transplant recipients than in the general population. Therefore, in order to identify patients at a higher risk for the development of cardiovascular disease in time, it is essential that transplant recipients undergo regular control of graft function, blood pressure, and metabolic parameters. A good graft function is important to increase the quality of life and decrease the mortality of this patient population.
Keywords
arterial hypertension; cardiovascular diseases; diabetes mellitus; immunosuppression; metabolic lipid metabolism disorder; transplantation
Hrčak ID:
118502
URI
Publication date:
3.3.2014.
Visits: 2.407 *