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Reumatizam, Vol. 60 No. 1, 2013.

Original scientific paper

Relationship between vitamin D status and bone mineral density in Croatian postmenopausal women

Nadica Laktašić-Žerjavić orcid id orcid.org/0000-0003-1279-3928 ; Clinic for Rheumatic Diseases and Rehabilitation, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Krešimir Rukavina ; School of Medicine, University of Zagreb, Zagreb, Croatia
Đurđica Babić-Naglić ; Clinic for Rheumatic Diseases and Rehabilitation, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Božidar Ćurković ; Clinic for Rheumatic Diseases and Rehabilitation, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Branimir Anić ; Department for Clinical Immunology and Rheumatology, Clinic for Internal Medicine, Clinical Hospital Centre Zagreb, Zagreb, Croatia
Dragica Soldo-Jureša ; University Clinic for Diabetes, Endocrinology and Metabolism Disorders “Vuk Vrhovac”, Clinical Hospital “Merkur”, Zagreb, Croatia

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Abstract

The aim of the study was to investigate correlation of vitamin D status meassured as 25-hydoxyvitamin D (25(OH)D) concentration with bone mineral density (BMD) in Croatian postmenopausal women. This study was based on the sample of 194 adult, postmenopausal women aged 50 years or over from Croatia. Assessment of 25(OH)D concentration and BMD by dual-energy x-ray absorptiometry (DXA) was performed to all participants. The average age of the participants in this study was 60.6 years. The average menopause duration was 11.4 years. Among the included participants only 13.9 % of women complied with diagnostic criteria for osteoporosis. Mean serum concentration of 25(OH)D was 49.1 nmol/L (±17.1 SD). The prevalence of severe vitamin D deficiency was significantly higher in participants with osteoporosis compared with participants with normal BMD (<30 nmol/L; 29.6 % vs. 9.8 %). Correlation between serum 25(OH)D concentration and BMD was significant and positive at the proximal femur (r=0.18; p=0.026), and at the femoral neck (r=0.15; p<0.001). The results of this study indicate significant and positive correlation between serum 25(OH)D concentration and BMD meassured at the proximal femur and at the femoral neck in Croatian postmenopausal women.

Keywords

bone density, mineral; calcifediol, 25-hydroxyvitamin D3; osteoporosis, postmenopausal

Hrčak ID:

123591

URI

https://hrcak.srce.hr/123591

Publication date:

1.6.2013.

Article data in other languages: croatian

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