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Reumatizam, Vol. 54 No. 1, 2007.

Original scientific paper

Comparative analysis of seronegative and seropositive rheumatoid arthritis regarding some epidemiological and anamnestic characteristics

Vjollca Sahatçiu-Meka ; Physical Medicine Department, Clinic for Orthopedics, Faculty of Medicine, University of Prishtina, Prishtina, Kosovo
Remzi Izairi ; Rheumatology Department, Clinic for Internal Medicine, Faculty of Medicine, University of Prishtina, Prishtina, Kosovo
Sylejman Rexhepi ; Rheumatology Department, Clinic for Internal Medicine, Faculty of Medicine, University of Prishtina, Prishtina, Kosovo
Suzana Manxhuka-Kerliu ; Institute for Pathology, Faculty of Medicine, University of Prishtina, Prishtina, Kosovo

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Abstract

Classifying patients into two subsets of the disease - seronegative RA and seropositive RA - has been the subject of many studies which aim to clarify this phenomenon - without any conclusive or acceptable answer so far. The aim of this prospective study was to establish a scientific comparative analysis between seronegative and seropositive rheumatoid arthritis (RA) regarding some epidemiological and anamnestic characteristics. The studied group consisted of seronegative patients with titers lower than 1:64 as defined by Rose-Waaler test, while the control group consisted of seropositive patients with titers of 1:64 or higher. All patients belonged to 2nd and 3rd functional class according to the ARA criteria, were between 25-60 years of age (Xb=49,96), with disease duration between 1-27 years (Xb=6,41). Education, residence, economic and living conditions did not show any significant statistical difference regarding sero-status. Familial clustering of RA confirmed higher susceptibility in the seropositive group (χ2=7,02; p<0,01). In both subsets banal diseases, psychic and physical trauma, weakness, and numbness of hands and legs dominated, without any statistical difference regarding sero-status. Some differences between groups regarding sex were noticed, but were not statistically significant, except regarding physical trauma, which was more pre­sent in seronegative females (χ2=8,05; p<0,01).

Keywords

rheumatoid arthritis; seropositive; seronegative; epidemiology; anamnesis

Hrčak ID:

125389

URI

https://hrcak.srce.hr/125389

Publication date:

1.7.2007.

Article data in other languages: croatian

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