Acta clinica Croatica, Vol. 46 No. 1, 2007.
Other
Adrenal Ganglioneuroma Associated with Primary Kidney Cancer. Report of Two Cases and Literature Review
Karla Tomić
Goran Štimac
Ognjen Kraus
Leonardo Tomić
August Mijić
Božo Krušlin
Abstract
Two cases of adrenal ganglioneuromas associated with ipsilateral primary kidney cancer, according to literature review a very rare combination, are presented. Both patients underwent adrenalectomy and nephrectomy. Specimens were formalin fixed, paraffin embedded, cut at 5 µm and routinely stained with hematoxylin and eosin. Primary antibodies to neurofilament protein and S-100 were used to confirm ganglion cells in the ganglioneuromas. Histopathological analysis revealed adrenal gland ganglioneuroma with ipsilateral kidney carcinoma. One of them was renal cell carcinoma and the other one was urothelial carcinoma of the renal pelvis. This combination of malignant kidney tumor and adrenal gland ganglioneuroma is extremely rare, and after literature review we concluded that both cases presenting this combination of tumors were probably incidental.
Keywords
Adenocarcinoma – pathology; Adenocarcinoma – surgery; Adrenal gland neoplasms – surgery; Ganglioneuroma – pathology; Ganglioneuroma – surgery; Kidney neoplasms – surgery
Hrčak ID:
12617
URI
Publication date:
30.3.2007.
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