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Acta Pharmaceutica, Vol. 65 No. 4, 2015.

Review article

https://doi.org/10.1515/acph-2015-0040

Practice implications and recommendations for managing codeine misuse and dependence

MICHAEL BERGIN ; Ph.D. School of Health Sciences, Waterford Institute of Technology, Waterford, Ireland
IAN NORMAN ; Ph.D. Kings College London, Florence Nightingale Faculty of Nursing & Midwifery, London, United Kingdom
MICHELLE FOLEY ; School of Health Sciences, Waterford Institute of Technology, Waterford, Ireland
RICHARD HARRIS ; H.I. Weldrick Ltd, Doncaster, United Kingdom
ANNA RAPCA ; H.I. Weldrick Ltd, Doncaster, United Kingdom
EILEEN RICH ; Alcohol, Tobacco and Other Drug Research Unit, South African. Medical Research Council, Pretoria, South Africa
MARIE-CLAIRE VAN HOUT ; Ph.D. School of Health Sciences, Waterford Institute of Technology, Waterford, Ireland

Full text: english pdf 569 Kb

page 351-364

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Abstract

Codeine, a weak opiate, requires increased pharmacovigilance relating to availability, heterogeneous nature of misuse, dependence and associated harm. A scoping review of literature on codeine was conducted using Arksey & O’Malley’s framework (1). Databases searched included PubMed, EBSCO Host, Science Direct, EMBASE, PsycINFO, Cochrane library and Medline from 1994 to 2014. Follow-up search strategies involved hand searching and searching of pharmaceutical, health, medical and drug related websites. Initial screening identified 3,105 articles with 475 meeting the inclusion criteria. Eight broad categories organised the literature, data charting and qualitative synthesis. This paper presents implications for practice and makes recommendations to address these issues. Themes identified relate to raising public and practitioner awareness, risk management, dispensing practices and monitoring and surveillance of codeine. Evidence to inform law enforcement, drug surveillance, public health initiatives, harm reduction approaches, pharmacy, clinical and treatment practices is warranted.

Keywords

codeine; over the counter; misuse; dependence; policy

Hrčak ID:

145091

URI

https://hrcak.srce.hr/145091

Publication date:

31.12.2015.

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