Acta clinica Croatica, Vol. 44 No. 1, 2005.
Original scientific paper
The Risk of Thyroid Malignancy in Patients with Solitary Thyroid Nodule Versus Patients with Multinodular Goiter
Neven Mateša
Irena Tabain
Zvonko Kusić
Abstract
The aim of the study was to compare the risk of thyroid malignancy in patients with a solitary thyroid nodule vs. patients with multinodular goiter. The prospective study included 406 patients who had one or more thyroid nodules and underwent ultrasound guided fine needle aspiration. There were 29 males and 377 females (male to female ratio 1:13). There were 117 (29%) patients (12 males and 105 females) with a solitary thyroid nodule, and 289 (71%) patients (17 males and 272 females) with multinodular goiter, age range 11-86 years, median 55 years. Upon cytologic examination definitive diagnosis of malignant tumor was made in six (5%) patients with a solitary thyroid nodule and in 15 (5%) patients with multinodular goiter. All patients with malignant tumors in both groups were females. It was concluded that there was no difference in the risk of thyroid malignancy between patients with a solitary thyroid nodule and patients with multinodular goiter.
Keywords
Thyroid neoplasms - pathology; Thyroid neoplasms - immunology; Carcinoma papillary; follicular - immunology; Goiter nodular - pathology; Biopsy needle - methods
Hrčak ID:
14228
URI
Publication date:
3.3.2005.
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