Veterinary Archives, Vol. 85 No. 5, 2015.
Original scientific paper
Arterial blood acidbase and electrolyte values in dogs: conventional and “strong ion” approach.
Josipa Kuleš
orcid.org/0000-0002-4945-4690
; Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Mirna Brkljačić
; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Martina Crnogaj
; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Dalibor Potočnjak
; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Darko Grden
; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Marin Torti
; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Vesna Matijatko
; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Vladimir Mrljak
; Clinic for Internal Diseases, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Renata Barić Rafaj
; Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia
Abstract
Arterial blood gas analysis is an essential part of diagnosing and managing an animal’s oxygenation and acid-base status. The aim of this study was to establish reference intervals for acid-base values and blood gases in clinically healthy dogs of different ages and sex using Stat Profi le Critical Care Xpress (CCX), and to provide an insight into the most appropriate approach to analyze complex acid-base abnormalities. Whole-blood arterial samples were obtained from 40 clinically healthy adult dogs of various breeds. Parameters of quantitative acidbase analysis (SIDCLIN, SIDAPP, SIDEFF, SIG) were calculated using the Stewart-Figge approach. Reference ranges were: pH 7.37 - 7.44, pCO2 22.62 - 34.52 mmHg, pO2 91.35 - 106.05 mmHg, A 106.33 - 120.12 mmHg, a/A 0.80 - 0.90 mmHg, AaDO2 -0.72 - 32.90 mmHg, HCO3 - 14.06 - 22.10 mmol/L, BEecf -12. 05 - 1. 61 mmol/L, BEb -9.7 - 0.46 mmol/L, SO2 94.31 - 100 %, pO2/FiO2 437.00 -507.45 mmHg, AG 5.49 - 19.67 mmol/L, ATOT 11.29 - 12.06 mmol/L, SIDCLIN 27.94 - 31.41 mmol/L, SIDAPP 26.00 - 31.60 mmol/L, SIDEFF 29.27 - 36.21 mmol/L, SIG 2.32 - 7.46 mmol/L. Reference values obtained on the CCX analyzer provide valuable baseline information for assessing new acid-base parameters and for interlaboratory comparisons. Differences compared with previously published reference values may be attributed largely to differences in methodology and sampling. The acid-base values determined in this study may be considered to be reference data for health control and disease diagnosis.
Keywords
acid-base values; electrolyte; dog; strong ion difference
Hrčak ID:
148140
URI
Publication date:
20.10.2015.
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