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Traumatic Hemolytic Anemias: Case Report and Review of the Literature

Filip Grubišić-Čabo
Vladimir Stančić

Abstract

Two patients with intravascular hemolysis are presented. One patient had traumatic hemolytic anemia after mechanical heart valve reimplantation, and the diagnosis was made rapidly and easily. In the other patient, the diagnosis was not so easy complex and time-consuming. This patient had both, traumatic hemolytic anemia caused by orthopedic prosthesis, and neutropenia. Fragmentation was caused by interaction of red blood cells with altered intravascular surfaces or by direct physical trauma to the cells due to excessive shear forces in the circulation. The following findings are seen in intravascular hemolysis: decreased hemoglobin, increased reticulocytes and lactic dehydrogenase, decreased serum haptoglobin, and presence of shizocytes in peripheral blood smear. Patients are considered to have intravascular hemolysis when lactic dehydrogenase is >460, along with the presence of two established criteria. If not causal, therapy is supportive.

Keywords

Anemia, hemolytic - etiology; Heart valve prosthesis, complications; Orthopedics, complications; Prosthesis, complications; Neutropenia, complications; Case reports

Hrčak ID:

14707

URI

https://hrcak.srce.hr/14707

Publication date:

1.3.2002.

Article data in other languages: croatian

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