Original scientific paper
The effect of tetracyclines on the mobilization of fluoride
M. Nedeljković
; Department of Toxicological Chemistry, University of Belgrade, Belgrade, Yugoslavia
V. Matović
; Department of Toxicological Chemistry, University of Belgrade, Belgrade, Yugoslavia
D. Soldatović
; Department of Toxicological Chemistry, University of Belgrade, Belgrade, Yugoslavia
Abstract
The teeth and the bone are the most important sites, of fluoride accumulation in the body. The effect of tetracycline and oxytetracycline on the mobilization of fluoride from these sites was examined. Investigations of chronic exposure to fluoride were carried out on rabbits which received 20 mg of fluoride/kg body weight by oral administration daily for 30 days. The results indicate that tetracyclines induce mobilization of deposited fluoride.
Keywords
Hrčak ID:
152779
URI
Publication date:
25.4.1989.
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