Acta clinica Croatica, Vol. 41 No. 4, 2002.
Other
Elimination of Microembolic Signals by Combined Anticoagulant and Antiplatelet Therapy
Evguenia Vassileva
Josette Le Floch-Rohr
Abstract
The effect of antithrombotic treatment on cerebral microembolism detected by transcranial Doppler sonography (TCD) in a case of internal carotid artery siphon stenosis is reported. A 58-year-old man suffered acute visual impairment associated with acute transient right upper limb paresis and paresthesia. Ultrasound examination of the neck arteries, TCD and digital subtraction angiography showed stenosis of the siphon of the left internal carotid artery. The patient was administered aspirin as antiplatelet therapy for 40 days, followed by anticoagulant therapy. Subsequently, he experienced many recurrent cerebral ischemic events. TCD monitoring performed on 4 occasions revealed microembolic signals (MES) in the ipsilateral middle cerebral artery. Aspirin was added to anticoagulant therapy. Once the combined anticoagulant and antiplatelet therapy had been introduced, no recurrent events were recorded anymore and no MES were detected. In this case, the detected MES proved to be in close relationship with recurrent cerebral ischemia, and were eliminated by combined anticoagulant and antiplatelet therapy.
Keywords
Intracranial embolism and thrombosis, therapy; Brain ischemia, complications; Carotid stenosis, complications; Carotid artery diseases, complications; Ultrasonography, Doppler, transcranial; Case report
Hrčak ID:
14756
URI
Publication date:
2.12.2002.
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