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Short communication, Note

Bronchial hyperreaktivity testing with metacholine in aluminium potroom workers

B. Ofner ; Medicinski centar Šibenik, Hrvatska
J. Marelja ; Zdravstvena stanica Tvornice lakih metala »B. Kidrič«, Sibenik, Hrvatska


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Abstract

Bronchial reactivity of 111 potroom workers in an aluminium plant was tested using the method of continuous nebulization and intermittent aerosol inhalation with a fixed number of non-dosimeter-regulated breaths at the same volume and different metacholine concentration. The method applied to the aluminium workers, asthmatic patients and healthy persons showed that a 46.5 cumulative dose unit is a limit value which can serve as a good indicator for distinguishing a hyperreactive person from a normoreactive one. With this metacholine dose, a significant decrease of FEV1 was measured in 23.4 % of potroom workers, 6.3 % of healthy persons and 1in 100 % of asthmatic persons. It is suggested that the application of non-specific bronchoprovocation challenge as a preemployment test could diminish, to some extent, the incidence of chronic bronchoobstructive disease in certain industnies.

Keywords

Hrčak ID:

153661

URI

https://hrcak.srce.hr/153661

Publication date:

30.6.1987.

Article data in other languages: croatian

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