Short communication, Note

Bronchial hyperreaktivity testing with metacholine in aluminium potroom workers

B. Ofner ; Medicinski centar Šibenik, Hrvatska
J. Marelja ; Zdravstvena stanica Tvornice lakih metala »B. Kidrič«, Sibenik, Hrvatska

Abstract

Bronchial reactivity of 111 potroom workers in an aluminium plant was tested using the method of continuous nebulization and intermittent aerosol inhalation with a fixed number of non-dosimeter-regulated breaths at the same volume and different metacholine concentration. The method applied to the aluminium workers, asthmatic patients and healthy persons showed that a 46.5 cumulative dose unit is a limit value which can serve as a good indicator for distinguishing a hyperreactive person from a normoreactive one. With this metacholine dose, a significant decrease of FEV1 was measured in 23.4 % of potroom workers, 6.3 % of healthy persons and 1in 100 % of asthmatic persons. It is suggested that the application of non-specific bronchoprovocation challenge as a preemployment test could diminish, to some extent, the incidence of chronic bronchoobstructive disease in certain industnies.

Keywords

Hrčak ID:

153661

URI

https://hrcak.srce.hr/153661

Publication date:

30.6.1987.

Article data in other languages: croatian

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