Acta clinica Croatica, Vol. 39 No. 4, 2000.
Professional paper
Specificities of Hematology Laboratory Findings in Major Operations for Head and Neck Tumors
Josip Kovač
Mladen Perić
Sonja Martinac-Djulepa
Mirko Ivkić
Vladimir Stančić
Biserka Raić
Dubravka Tonković
Sanja Krapinec
Mladen Novkoski
Abstract
The aim of the study was to determine the incidence of coagulation disorders and possible differences between patients operated on for head and neck tumors with and without blood transfusion treatment. The study included 31 patients divided into two groups: 16 patients with and 15 patients without intraoperative administration of blood transfusion. The following laboratory parameters were monitored: leukocyte count, erythrocyte count, hemoglobin, hematocrit, platelet count, activated partial thromboplastin time, prothrombin time, fibrinogen, thrombin time, and fibrinolysis. Data were statistically analyzed by Student’s t-test for dependent and independent samples, and by simple correlation. The results showed prothrombin time to be statistically significantly reduced postoperatively in both patient groups, while fibrinolysis was statistically significantly accelerated in the group of patients who received intraoperative blood transfusion. Accordingly, in patients administered blood transfusion during the surgery, fibrinolysis was statistically significantly accelerated in comparison with their preoperative values. In the group of patients who did not receive intraoperative blood transfusion, fibrinolysis remained within the physiological range.
Keywords
Head and neck neoplasms, surgery; Neoplasms, blood; Fibrinolysis, physiology
Hrčak ID:
14979
URI
Publication date:
1.12.2000.
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