Original scientific paper

Familial Appearance of Primary Open Angle Glaucoma

Katia Novak-Lauš
Jadranka Koršić
Goran Benčić
Zdravko Mandić

Abstract

The aim of the study was to point out the role of inheritage of primary open angle glaucoma (POAG) and frequency of POAG among other glaucoma diseases. The study included 52 relatives from 12 families with family history of POAG through 3 generations. The examination consisted of complete ophthalmologic status, automated perimetry and optic nerve photography. A detailed anamnesis and family trees were taken. Individuals were diagnosed with POAG if they fulfilled two or three of the criteria for making a diagnosis: the level of intraocular pressure visual field loss or characteristic disc appearance. Subjects were considered "suspected POAG" if they fulfilled only one of the preceding three criteria. All three parameters had to be normal for an individual to be considered unaffected. Seven relatives (l2%) were diagnosed with POAG; fifteen (29%) relatives were classified as glaucoma suspects. Siblings of POAG patients had the highest risk of POAG developing compared with children or other blood relatives. The study presented results of investigation the frequency of POAG among other glaucoma diseases and 16% patients had a family history of POAG at least in 3 generations. Detailed anamnesis confirms familial appearance of POAG and examination of all available members enables the discovery of new cases (12%).

Keywords

Glaucoma; heredity

Hrčak ID:

15002

URI

https://hrcak.srce.hr/15002

Publication date:

1.11.2002.

Article data in other languages: croatian

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