Professional paper

Poisoning with a large dose of digoxin

Z. Duraković ; Klinika za unutrašnje bolesti s poliklinikom Rebro Medicinskog fakulteta Sveučilišta u Zagrebu, Hrvatska
M. Gjurašin ; Klinika za unutrašnje bolesti s poliklinikom Rebro Medicinskog fakulteta Sveučilišta u Zagrebu, Hrvatska
F. Plavšić ; Zavod za kliničko-laboratorijsku dijagnostiku, Klinički bolnički centar u Zagrebu, Zagreb, Hrvatska

Abstract

The paper describes the course of ilness in a 63-year-old woman who ingested 10 mg of medigoxin with suicidal intent. The first signs of poisoning were nausea and vomiting. The electrocardiogram showed sings of atrioventricular dissociation and atrial fibrillation, and serum digoxin concentration was 19.9 nmol/L, The partien1: also had sings of acute renal failure with a renal failure index of 3.9. Digoxin half-life was between 30 and 90 hours, depending on renal damage. ECG signs of digitalis intoxication were in correlation with the corrected 0-T-interva! and P-T-0 index. On the seventh day of the ilness the serum digoxin concentration was 2.5 nmol/L.

Keywords

Hrčak ID:

157064

URI

https://hrcak.srce.hr/157064

Publication date:

11.4.1985.

Article data in other languages: croatian

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