Conference paper

PSYCHOBIOLOGICAL MODEL OF PERSONALITY AND PSYCHOPHARMACOTHERAPY OUTCOMES IN TREATMENT OF DEPRESSION AND SCHIZOPHRENIA

Branka Aukst Margetić orcid.org/0000-0002-7830-224X ; University Hospital Centre Zagreb, Department of Psychiatry, Zagreb, Croatia
Miro Jakovljević orcid.org/0000-0003-0420-357X ; University Hospital Centre Zagreb, Department of Psychiatry, Zagreb, Croatia

Abstract

In distinguishing why some patients respond and other do not respond to treatments arraised the clinically very important body
of research considering weather patients’ personality characteristics might predict outcomes of pharmacotherapeutic treatment.
Personality can be a predictor of a psychiatric disorder either owing to their common genetic background or because it enhances
exposure of the subject to environmental risk factors.
The results of the studies using psychobiological model are reviewed. The studies show that personality temperament dimension
Harm Avoidance and character dimension Self-directedness predict outcomes of the pharmacological treatment of depression, but
the result for other psychiatric disorders are sparse.
The studies are not straightforward in recommendations for treatment choice dependent of personality dimensions.

Keywords

personality - psychobiological model – depression – schizophrenia – adherence - treatment-resistance

Hrčak ID:

161216

URI

https://hrcak.srce.hr/161216

Publication date:

17.9.2013.

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