Liječnički vjesnik, Vol. 134 No. 7-8, 2012.
Review article
IDIOPATHIC EOSINOPHILIC PLEURAL EFFUSION – CASE REPORT
Joško Mitrović
Branimir Anić
Jadranka Morović Vergles
Abstract
Eosinophilic pleural effusion (EPE) is defined as exudative effusion that contains at least 10% eosinophils.1 The most common conditions associated with EPE are malignancy, infections, post-traumatic and post-surgical conditions, hypersensitivity, systemic autoimmune diseases, congestive heart failure, cirrhosis, pulmonary embolus, asbestosis and drug induced EPE.2–4 Pleural effusion accompanying autoimmune diseases is most common in patients with systemic lupus erythematosus,5,6 rheumatoid arthritis,6 howewer it rarely occurs in patients with progressive systemic sclerosis and polymiositis.6 EPE has rarely been reported in association with Churg Strauss syndrome.7 In about 14–25% of patients EPE can be defined as idiopathic when diagnostic procedures failed to identify the etiology.2–4 Treatment of EPE is based on the treatment of primary disease and with idiopathic form a good answer is reached using glucocorticoids. In this case report we presented the patient with idiopathic eosinophilic pleural effusion where in diagnostic procedures we excluded other diseases or conditions in which EPE can be shown, and with applied therapy with methylprednisolone we achieved excellent clinical response and final healing.
Keywords
Pleural effusion – diagnosis, drug therapy; Eosinophilia – diagnosis, drug therapy; Methylprednisolone – therapeutic use; Anti-inflammatory agents – therapeutic use
Hrčak ID:
172435
URI
Publication date:
27.8.2012.
Visits: 2.072 *