Short communication, Note

Acute toxicity of some salts of nicotine, N-methylpyrrolidine and pyridine

B. Nikolin ; Institut za herniju i Institut za farmakologiju Medicinskog fakulteta, Sarajevo
B. Bošković ; Institut za herniju i Institut za farmakologiju Medicinskog fakulteta, Sarajevo
M. Deželić ; Institut za herniju i Institut za farmakologiju Medicinskog fakulteta, Sarajevo

Abstract

Acute toxicity of some newly synthesized salts of nicotine, N-methylpyrrolidine and pyridine was studied in mice. Acute toxicity of nicotine compounds with gallic, gentisic, oxalic, p-aminosalicylic and p-nitrobenzoic acid proved higher than that of the pure nicotine, but it was mainly due to the toxicity of nicotine itself. N-methylpyrrolidine-gallate was found to produce certain protective effect in mice poisoned by nicotine-gentisinate.

Keywords

Hrčak ID:

178557

URI

https://hrcak.srce.hr/178557

Publication date:

22.9.1966.

Article data in other languages: bosnian

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