Cardiologia Croatica, Vol. 12 No. 7-8, 2017.
Professional paper
https://doi.org/10.15836/ccar2017.307
Childhood obesity and kidney health.
Bernardica Valent Morić
orcid.org/0000-0001-6516-5955
; University Hospital Centre “Sestre milosrdnice”, Zagreb, Croatia
Abstract
The prevalence of chronic kidney disease increases in parallel with the growing prevalence of obesity, indicating an overt causal relationship of obesity and kidney disease. Nowadays, it is well known that prenatal factors, gestational age and birth mass, as well as dietary pattern from the earliest childhood have long-term effects on the individual’s susceptibility to develop obesity, diabetes mellitus, cardiovascular disease and chronic kidney disease. Obesity exerts unfavorable impact on primary kidney disease and is related to early onset of glomerulomegaly and renal hemodynamic changes due to glomerular hyperfiltration, albuminuria and elevated arterial pressure. Obese individuals with additional risk factors may develop obesity-related glomerulopathy. Recently, methods have been developed for early detection of kidney injury related to obesity, based on the fact that tubular lesions precede the onset of albuminuria, i.e. prior to glomerular injury. Body mass reduction, i.e. normalization, is the basic method in the treatment of renal complications of obesity.
Keywords
obesity; kidney; children; glomerulopathy; arterial hypertension
Hrčak ID:
185343
URI
Publication date:
21.7.2017.
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