Medicinski vjesnik, Vol. 37 No. (1-4), 2005.
Professional paper
Results of treatment for patients with carcinoma in situ of the upper urinary tract
Damir Puškar
Željko Bartolin
Goran Bedalov
Ivan Savić
Zoran Peršec
Franjo Jurenec
Abstract
Aim: to present the results of treatment for three (3) patients with transitional cell carcinoma "in situ" of the upper urinary tract (one patient with bilateral carcinoma and two patients with solitary kidney carcinoma) by using Bacillus Calmette-Guerin instillation.
Material and methods: diagnostic criteria of upper urinary tract carcinoma "in situ" were positive urinary cytology, positive urinary cytology in urine sample from the pyelocaliceal system, negative intravenous pyelography, as well as negative multiple random biopsy of the urinary bladder. After placing a 6-Chariere JJ prothesis, Bacillus Calmette-Guerin (80mg) in 40ml 0.9% NaCl solution was instilled into the urinary bladder once a week over a 6-week-period. Urinary cytology was done every 3 months during the first year and later on every 6 months.
Results: Urine cytological findings were found positive in one (1) patient after 9 months. The findings were still negative in the second patient after 30 and in the third patient after 42 months.
Discussion: Bacillus Calmette-Guerin instillation presents an acceptable method of treatement for transitional cell carcinoma "in situ" of the upper urinary tract, particullary in patients with solitary kidney.
Keywords
Transitional cell carcinoma "in situ"; Kidney; Ureter; Treatment
Hrčak ID:
190876
URI
Publication date:
1.12.2005.
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