Medicinski vjesnik, Vol. 37 No. (1-4), 2005.
Professional paper
Results' analysis of 12-core and 8-core protocol in ultrasound guided transrectal prostate biopsy at the department of urology in Varaždin
Tonći Dujmović
Goran Benko
Krunoslav Benčić
Zoran Filipan
Damir Štajcar
Abstract
Aims: With implementation of 12- versus 8-core ultrasound guided transrectal prostate biopsy protocol we tried to improve prostate cancer detection.
Material and methods: Transrectal ultrasound guided prostate biopsy was performed in 149 patients with PSA and/or clinical suspection on prostate cancer. 76 of them underwent 8-core biopsy protocol, and 73 underwent 12-core biopsy protocol.
Results: In the group with 8-core biopsy protocol prostate cancer was histologically detected in 26 patients (34,2%). 40 patients had only PSA elevation without DRE and/or TRUS suspection, and 9 of them were positive (22,5%). 44 patients had PSA elevation 4-10 ng/ml and 10 of them were positive (22,7%). In the group of patients with elevation of PSA 4-20 ng/ml 21 of 64 (32,8%) were positive. In the group with 12-core biopsy protocol, 30 of 73 (41,1%) patients were positive. Among patients who only had elevated PSA, 6 of 32 were positive (18,7%). With PSA elevation 4-10 ng/ml, 9 of 36 patients were positive (25%). And in the group with PSA elevation 4-20 ng/ml, 17 of 55 (30,9%) patients were positive for prostate cancer.
Discussion: 12-core biopsy protocol did not significantly improve prostate cancer detection. As a matter of fact, additional prostate biopsy cores were never alone positive in histologically detected prostate cancers.
Keywords
Department of Urology in Varaždin; Results’ analysis; 12-core and 8-core biopsy protocol; Ultrasound guided transrectal prostate biopsy
Hrčak ID:
190936
URI
Publication date:
1.12.2005.
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