Medicinski vjesnik, Vol. 42 No. (3-4), 2010.
Original scientific paper
Bone mineral density in adolescents with chronic kidney disease: a follow-up study
Selma Cvijetić Avdagić
Jasna Slaviček
Iva Karačić
Zvonimir Puretić
Petar Kes
Abstract
The aim of this follow-up study was to analyze the change of bone mineral density in adolescents with chronic kidney disease and to determine the influence of height, weight and bone size on bone density The study included 30 patients, aged 13.513.5 years. Regular biochemistry included serum calcium, phosphorus and PTH. Bone mineral density (BMD) was measured by dual energy absorptiometry (DXA). The mean time between baseline and follow up measurements was 15.7 months. Despite the significant increase in weight and height in all participants, anthropometric variables were below one standard deviation from reference values in both measurements (Z value < -1, for height and weight). After correction for height and weight, the increase of BMAD between two measurements was not significant. It is necessary to correct the bone density for height and weight in children with chronic kidney disease, due to their retarded growth velocity.
Keywords
density; Kidney failure, chronic; Dialysis; Adolescent; Follow-up studies
Hrčak ID:
191925
URI
Publication date:
1.12.2010.
Visits: 1.081 *