Medicinski vjesnik, Vol. 28 No. (1-4), 1996.
Original scientific paper
Perioperative blood transfusion as a possible prognostic factor in laryngeal cancer
Stjepan Grabovac
Stjepan Simović
Ivan Cikoja
Abstract
A retrospective study was conducted on the influence of perioperative blood transfusion on the course and outcome of the disease with 116 patients on whom a surgical procedure had been performed at the ENT department, Zagreb University Hospital, in the period from 1985 to 1990. The group under research in cluded only the patients with laryngeal cancer in the 2nd do 4th stage, be cause patients in the 1st stage of the disease had neither received blood transfusion nor had a recurrence. Recurrence, however, was noted in 73 (62.9 %) patients i.e. in 42 (70 %) patients who received blood transfusion perioperatively and in 31 (55.4 %) patients who did not received blood transfusion. The difference was not statistically significant. During the first post-operative year 73 recurrences occurred, 33 (45.2%) of which in the group that received perioperative blood transfusion (i.e., 78.6% of the 42 persons who received perioperative blood transfusion and had a recurrence in the three-year observation period; the remaining 9 recurrences occurred during the 2nd year of
the observation), and 16 during the remaining two years of the observation. Earlier recurrences in the patients who received perioperative blood transfusion are statistically significant (x2 12.379; DF 2; P<0.001).
Keywords
perioperative blood transfusion; recurrence; laryngeal carcinoma; prognostic factors
Hrčak ID:
192484
URI
Publication date:
1.12.1996.
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