Original scientific paper

The Activity Coefficients of Amino Acids and Peptides in Aqueous Solutions Containing Guanidinium Chloride

S. Lapanje ; Department of Chemistry and Chemical Engineering, Edvard Kardelj University, 61000 Ljubljana, Yugoslavia
A. Južna ; Department of Chemistry and Chemical Engineering, Edvard Kardelj University, 61000 Ljubljana, Yugoslavia
V . Vlachy ; Department of Chemistry and Chemical Engineering, Edvard Kardelj University, 61000 Ljubljana, Yugoslavia
G. Vesnaver ; Department of Chemistry and Chemical Engineering, Edvard Kardelj University, 61000 Ljubljana, Yugoslavia

Abstract

Six systems of the type amino acid- or peptide-guanidinium
chloride-water have been investigated over wide solute molality
ranges using vapor pressure osmometry. The amino acids used
were glycine and L-leucine, while the peptides were diglycine,
triglycine, glycyl-L-leucine and L-leucyl-L-leucine. Equations for
the ratios of the activity coefficients of these compounds in the
salt solutions and water, respectively, were obtained in terms of
the molalities of the solutes. The activity coefficient ratios for
glycine are not much below one, whereas those for i.-leucine are
considerably smaller reflecting the presence of the leucyl side
chain. The activity coefficient ratios for the peptides are generally
smaller than those for the amino acids which can be attributed to
. the presence of the peptide group.

Keywords

Hrčak ID:

194438

URI

https://hrcak.srce.hr/194438

Publication date:

15.3.1981.

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