Preliminary communication

A Chiral Phosphine (CRC-PHOS) Derived from ( + )-Champhanic Acid. A New Ligand for Homogeneous Asymmetric Hydrogenation

G. Comisso ; CRC, Chemicai Research Company, 33048 San Giovanni al Natisone (UD) Italy
A. Sega ; CRC, Chemicai Research Company, 33048 San Giovanni al Natisone (UD) Italy
V. Šunjić ; CRC, Chemicai Research Company, 33048 San Giovanni al Natisone (UD) Italy

Abstract

The lactone of 1S,3S-1-hydroxy-1-diphenylphosphinomethyl-
2,2,3-tri-methyl-cyclopentan-3-carboxylic acid (4, CRC-PHOS) was
prepared from ( + )-camphanic acid methylester 1, and its complex
salt [Rh(CRC-PHOS)2NBD] · CI04 • THF (5) was isolated. The latter
exhibited rather a high rate, but low enantioselectivity in the first
attempt at asymmetric hydrogenation.

Keywords

Hrčak ID:

194538

URI

https://hrcak.srce.hr/194538

Publication date:

15.11.1980.

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