Croatica Chemica Acta, Vol. 45 No. 1, 1973.
Conference paper
Surfaces and the Folding of Polypeptide Chains
A. G. Walton
; Case Western Reserve University, Division of Macromolecular Science, Cleveland, Ohio 44106, U.S.A.
Abstract
An approach to the folding of polypeptide chains is explored
theoretically and compared with experimental data. It appears that
in synthetic chain folded polypeptide crystals, the fold period is
statistically determined by the energetics of nucleation.
The broader question of chain folding in globular proteins is
presented and an equation derived which shows that the fold length
is likely to be a function mainly of the particular fold energy and
the driving free energy derived from long range stabilization forces.
Keywords
Hrčak ID:
197046
URI
Publication date:
15.6.1973.
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