Professional paper
https://doi.org/10.22514/SV141.032018.16
Treatment of non-oliguric hyperkalaemia with inhaled salbutamol in premature infants with severe respiratory distress syndrome
MAJA PAVCNIK
; Department of Paediatric Surgery and Intensive Care University Medical Centre Ljubljana Bohoriceva 20, 1525 Ljubljana, Slovenia
EDA VIDMAR
Abstract
Non-oliguric hyperkalaemia (NOHK) in
neonates is defned as a plasma potassium
level > 6.5 mmol/L in the presence of urine
output ≥ 1 mL/kg/h during the frst 72
hours of life. It is characterized by a rapid
rise of serum potassium to excessively high
values, a high risk of cardiac arrhythmias
and no occurrence afer 72 hours of birth.
NOHK commonly occurs in premature
neonates, especially in those with a gestational
age <28 weeks, with only a few
reports of this entity in moderate or late
preterm neonates. Te efectiveness and
safety of diferent treatments for NOHK
is uncertain and currently there is no frm
treatment recommendation. We describe
the case of a moderately premature neonate
(32+ 2 weeks gestation), with severe
neonatal respiratory distress syndrome,
who developed NOHK that was treated
with inhaled salbutamol. When salbutamol
is used for the treatment of NOHK, an
initial paradoxical rise in potassium levels
should always be taken into account to
avoid cardiac arrhythmias.
Keywords
non-oliguric hyperkalaemia; premature; infants; salbutamol; hyperkalaemia
Hrčak ID:
200411
URI
Publication date:
1.6.2018.
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