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Acta clinica Croatica, Vol. 57. No. 3., 2018.

Other

https://doi.org/10.20471/acc.2018.57.03.23

Multifocal Motor Neuropathy: Case Reports

Edin Jusufović ; Department of Neurology, Tuzla University Clinical Centre, Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina
Osman Sinanović orcid id orcid.org/0000-0001-8957-7284 ; Department of Neurology, Tuzla University Clinical Centre, Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina
Sanela Zukić ; Department of Neurology, Tuzla University Clinical Centre, Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina
Adnan Burina ; Department of Neurology, Tuzla University Clinical Centre, Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina
Zlatka Džinić Jusufović ; Department of Neurology, Tuzla University Clinical Centre, Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina
Alma Šakić ; Department of Neurology, Tuzla University Clinical Centre, Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina

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Abstract

Multifocal motor neuropathy (MMN) is a chronic demyelinating neuropathy mainly characterized by multifocal distribution; affecting only motor nerve fibers of two or more peripheral nerves, with the absence of symptoms and signs of upper motor neuron; chronic, sometimes cascading progressive course; demyelination with partial block of motor conduction; immune-mediated pathogenesis and good response to intravenous immunoglobulin treatment (IVIG). The diagnosis of MMN is based on clinical, laboratory and electrophysiological characteristics. Steroids are ineffective in MMN and may lead to worsening of the disease. Similarly, therapeutic plasma exchange is negligibly effective in this neuropathy. However, more than 80% of patients with MMN experience improvement after IVIG. We present our three cases of MMN with positive response to IVIG.

Keywords

Polyneuropathies; Demyelinating diseases; Peripheral nerves; Motor neurons; Immunoglobulins, intravenous

Hrčak ID:

216192

URI

https://hrcak.srce.hr/216192

Publication date:

1.9.2018.

Article data in other languages: croatian

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