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Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, Vol. 73 No. 1, 2019.

Review article

MANAGEMENT OF CARDIOVASCULAR RISK FACTORS IN RHEUMATOID ARTHRITIS

MARIJA GLASNOVIĆ ; J. J. Strossmayer University in Osijek, Faculty of Medicine, Osijek, Osijek University Hospital Centre, Department of Internal Medicine, Osijek, Croatia
ALEKSANDAR VČEV ; J. J. Strossmayer University in Osijek, Faculty of Medicine, Osijek, Osijek University Hospital Centre, Department of Internal Medicine, Osijek, Croatia
ELIZABETA HORVATIĆ ; Tomislav Bardek General Hospital, Department of Pathology and Cytology, Koprivnica, Croatia
ŽELJKA KOLAK ; Vinkovci General Hospital, Vinkovci, Croatia
VALENTINA MATIJEVIĆ ; Sestre milosrdnice University Hospital Centre, Department of Rheumatology, Physical Medicine and Rehabilitation, Zagreb, Croatia
DOMINIK GJONI ; J. J. Strossmayer University in Osijek, Faculty of Medicine, Osijek, Croatia
STEFAN GJONI ; J. J. Strossmayer University in Osijek, Faculty of Medicine, Osijek, Croatia
FABIAN GJONI ; J. J. Strossmayer University in Osijek, Faculty of Medicine, Osijek, Croatia

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Abstract

Patients with infl ammatory rheumatic diseases, particularly rheumatoid arthritis (RA), have a signifi cantly increased risk of cardiovascular (CV) disease compared to the general population. This particularly refers to the increased risk of myocardial infarction and ischemic heart disease. CV events and mortality rate in RA are by 40%-50% higher as compared with general population and the risk of ischemic heart disease is slightly higher than that of stroke. The risk increase in RA is initiated by a complex interaction between traditional and non-traditional factors of CV risk, where infl ammation, through direct or indirect harmful effects on vascular system, plays an important role. The infl ammation in RA is crucial for the development of CV risk and is an independent risk factor for the increased incidence of CV diseases. Patients having stronger disease activity in RA have an increased risk of developing heart failure. Doctors of medicine should be aware of the high CV risk and provide good control and treatment of CV diseases in RA patients.

Keywords

rheumatoid arthritis; cardiovascular risks; inflammation

Hrčak ID:

218947

URI

https://hrcak.srce.hr/218947

Publication date:

4.4.2019.

Article data in other languages: croatian

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