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https://doi.org/10.20471/acc.2019.58.01.22

Successful Treatment of Acute Disseminated Encephalomyelitis (ADEM) by Prompt Usage of Immunoglobulins – Case Report and Review of the Literature

Ana Repić-Buličić ; Department of Neurology, Split University Hospital Centre, Split, Croatia
Petar Filipović-Grčić ; Department of Neurology, Split University Hospital Centre, Split, Croatia
Eni Jadrijević ; Department of Neurology, Split University Hospital Centre, Split, Croatia
Pavao Jurinović ; Department of Neurology, Split University Hospital Centre, Split, Croatia
Marina Titlić ; Department of Neurology, Split University Hospital Centre, Split, Croatia

Abstract

Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system that usually affects children and young adults. It most commonly has a monophasic course, although relapses are reported. Clinical presentation of the disease
includes encephalopathy and multifocal neurological deficits. There are no established reliable criteria for diagnosis of ADEM and sometimes it is difficult to distinguish it from first attack of multiple sclerosis, especially in adults. The diagnosis of ADEM is based on clinical, radiological and laboratory findings. In the treatment of ADEM, high doses of corticosteroids, plasmapheresis and immunoglobulins are used. We report a case of a young adult female patient with ADEM who fully recovered after prompt administration of high dose methylprednisolone and immunoglobulins.

Keywords

Encephalomyelitis, acute disseminated; Immunoglobulins; Adrenal cortex hormones; Methylprednisolone; Case reports

Hrčak ID:

220915

URI

https://hrcak.srce.hr/220915

Publication date:

1.3.2019.

Article data in other languages: croatian

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