Original scientific paper

Assessment of the parameters of systemic inflammatory response syndrome in dogs

Petra Dmitrović orcid.org/0000-0002-7162-6110 ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Dmitrij Kvitka ; Small Animal Clinic, Lithuanian University of Health Sciences, Kaunas, Litva
Gintaras Zamokas ; Small Animal Clinic, Lithuanian University of Health Sciences, Kaunas, Litva
Dražen Vnuk ; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska

Abstract

Systemic inflammatory response syndrome (SIRS) is a clinical manifestation of systemic inflammation induced by various causes. Some of the most common include sepsis, trauma, burns and neoplasia. This syndrome is often related to increased morbidity and mortality in animals. This study included ten dogs that developed signs of SIRS and that were admitted to the Clinic for surgery, orthopaedics and ophthalmology due to trauma or requiring surgical intervention in the abdominal cavity. All data was collected in the period from 14 August 2013 to 17 August 2015. Systemic inflammatory response syndrome was diagnosed based on the fulfilment of at least two of the following four criteria: hypo- or hyperthermia, tachycardia, tachypnea, leukocytosis or leukopenia or a left shift. Blood samples were collected from all
ten dogs for haematological analysis, and from five dogs for serum biochemistry analysis. All dogs were re-evaluated clinically during hospitalization. Clinical, haematological and serum biochemistry data were examined. This study showed that the most frequent SIRS parameter was leukocytosis, followed by tachypnea. However, no link was found between specific SIRS parameters and a fatal outcome, nor between the number of occurring parameters and a fatal outcome. A much higher survival rate was observed in this study than in the literature. Considering the variability of the SIRS criteria and its unreliability in dogs, further study should be aimed at determining the relevant diagnostic and prognostic factors. poveznica između broja utvrđenih pokazatelja i letalnog ishoda. Utvrđena je znatno veća stopa preživljavanja nego u drugim istraživanjima. S obzirom na varijabilnost kriterija te nepouzdanost pokazatelja SSUO-a u pasa, potrebna su daljnja istraživanja kojima bi se utvrdili dijagnostički i prognostički značajniji pokazatelji.

Keywords

systemic inflammatory response syndrome (SIRS); sepsis; leukocytosis; dogs

Hrčak ID:

222659

URI

https://hrcak.srce.hr/222659

Publication date:

4.12.2017.

Article data in other languages: croatian

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