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Review article

https://doi.org/10.26800/LV-141-7-8-32

Patient with myelodysplastic syndrome in emergency department

Ingrid Prkačin orcid id orcid.org/0000-0002-5830-7131 ; Klinička bolnica Merkur, Klinika za unutarnje bolesti, Zagreb Sveučilišta
Inga Mandac Rogulj orcid id orcid.org/0000-0001-5234-9464 ; Klinička bolnica Merkur, Klinika za unutarnje bolesti, Zagreb
Višnja Mandac Bajan ; Neuropsihijatrijska bolnica „Dr. Ivan Barbot“, Popovača
Ana Planinc Peraica ; Klinička bolnica Merkur, Klinika za unutarnje bolesti, Zagreb;Medicinski fakultet Sveučilišta u Zagrebu, Zagreb
Gordana Cavrić ; Klinička bolnica Merkur, Klinika za unutarnje bolesti, Zagreb
Dean Mileta ; Klinička bolnica Merkur, Klinika za unutarnje bolesti, Zagreb


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Abstract

Myelodysplastic syndromes (MDS) are a group of clonal disorders arising from hematopoietic stem cells and are generally characterized by inefficient hematopoiesis and dysplasia. The International Prognostic
Scoring Sytem (IPSS) is an important standard for assessing prognosis of primary untreated adult patients with myelodysplastic syndromes (MDS). Ineffective hematopoiesis leading to anemia is the most common cause of the arrival of patients with MDS in the emergency room . Patients with MDS have a number of associated conditions
such as chronic kidney disease and hypertension, and may be present as acute coronary syndrome. We report a case of a 83-year-old female with MDS that was diagnosed in 2014 and had no specific treatment. She presented to the emergency department at the beginning of 2016 because of epigastric and chest pain that began in the morning. Diagnosis of subacute STEMI with a scar formed on front wall and elevated high-sensitivity troponin (hsTnI) which amounted to 1,369 ng / L (reference value < 15.6 ng / L) was made , and the patient was
hospitalized in the Coronary Care Unit . The care for this population of patients, mainly elderly, in the emergency department requires a comprehensive approach due to the presence of associated conditions such as hypertension, chronic kidney disease and ischemic heart disease. Cardiovascular diseases (CVD) are the leading cause of
death in all countries worldwide.

Keywords

MYELODYSPLASTIC SYNDROMES – complications; ANEMIA, REFRACTORY – etiology; ST ELEVATION MYOCARDIAL INFARCTION – complications, diagnosis; TROPONIN – blood; NATRIURETIC PEPTIDE, BRAIN – blood; EMERGENCIES; COMORBIDITY

Hrčak ID:

225772

URI

https://hrcak.srce.hr/225772

Publication date:

27.9.2019.

Article data in other languages: croatian

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