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Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, Vol. 73 No. 4, 2019.

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ALLERGY TO HYPOALLERGENIC METALS

OLESIA BESH ; Nacionalni medicinski fakultet Danylo Halytsky Lviv, Klinika za internu medicinu 2, Lviv, Ukraine
OLENA SOROKOPUD ; Nacionalni medicinski fakultet Danylo Halytsky Lviv, Klinika za internu medicinu 2, Lviv, Ukraine
OKSANA MATSYURA ; Nacionalni medicinski fakultet Danylo Halytsky Lviv, Klinika za internu medicinu 2, Lviv, Ukraine
MARTA KONDRATYUK ; Nacionalni medicinski fakultet Danylo Halytsky Lviv, Klinika za internu medicinu 2, Lviv, Ukraine
OKSANA SLABA ; Nacionalni medicinski fakultet Danylo Halytsky Lviv, Klinika za internu medicinu 2, Lviv, Ukraine
OLGA KOROLYUK ; Nacionalni medicinski fakultet Danylo Halytsky Lviv, Klinika za internu medicinu 2, Lviv, Ukraine
OREST KOMARYTCIA ; Nacionalni medicinski fakultet Danylo Halytsky Lviv, Klinika za internu medicinu 2, Lviv, Ukraine
DMYTRO BESH ; Nacionalni medicinski fakultet Danylo Halytsky Lviv, Klinika za internu medicinu 2, Lviv, Ukraine

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Abstract

Every year the number of people with allergic diseases significantly increases worldwide. It might be explained by many factors, e.g., environmental pollution, nutrition and food quality, uncontrollable use of medications, quality of home cleaning or use of excessive amount of chemicals. The main food allergens are cow's milk, eggs, soybeans, peanuts, seafood and fish. Severe allergic reactions may be drug induced, most commonly by antibiotics, ACE inhibitors, and non-steroidal anti-inflammatory drugs. Some substances, which until recently were considered hypoallergenic, are reported to cause hypersensitivity with increasing incidence. These include some metals, such as titanium, cobalt, chromium and others. Titanium is widely used in orthopaedics, traumatology, dentistry, and other branches of medicine because it is highly resistive to corrosion, hypoallergenic, inert, and non-toxic to the human body. Unfortunately, the diagnosis of metal allergy is not widely available today. Since not all allergic reactions mediated by IgE-dependent mechanism, serological diagnosis becomes impossible. The diagnostic option in such cases are patch tests with possible culprit allergens.

Keywords

allergy; metal; angioedema

Hrčak ID:

231183

URI

https://hrcak.srce.hr/231183

Publication date:

5.12.2019.

Article data in other languages: croatian

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