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Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, Vol. 74 No. Supl 1, 2020.

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METFORMIN POISONING AND METFORMIN ASSOCIATED LACTACIDOSIS

JASMIN HAMZIĆ orcid id orcid.org/0000-0003-2726-4308 ; Zagreb University Hospital Centre, Emergency Department, Zagreb, Croatia
KATJA KUDRNA-PRAŠEK ; Zagreb University Hospital Centre, Emergency Department, Zagreb, Croatia
IVAN GORNIK ; Zagreb University Hospital Centre, Emergency Department, Zagreb, Croatia

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Abstract

The objective of this case report is to present a patient with metformin poisoning, and to highlight treatment and potential pitfalls. A 65-year-old patient was admitted to Emergency Department (ED) with head injury. He was hypoglycemic and received IV glucose, but altered consciousness persisted. His arterial blood gas analysis showed deep acidemia with high lactate levels. After aggressive treatment, his pH improved, and after prolonged 36-hour observation in ED, lactate levels dropped to normal, he was feeling better and was discharged home. This was an unusual presentation of metformin toxicity, which is usually life threatening, therefore we try to point out how to manage and recognize patients like this one in ED.

Keywords

metformin; toxicity; lactacidosis

Hrčak ID:

236630

URI

https://hrcak.srce.hr/236630

Publication date:

16.3.2020.

Article data in other languages: croatian

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