Professional paper
https://doi.org/10.21860/medflum2020_241522
The effect of treatment of knee joint osteoarthritis using stem cells – early results
Vjeran Rapan
; Medicinski fakultet, Sveučilište u Osijeku, Osijek, Hrvatska
Domagoj Rapan
; Medicinski fakultet, Sveučilište u Osijeku, Osijek, Hrvatska
Saša Rapan
; Medicinski fakultet, Sveučilište u Osijeku, Osijek, Hrvatska
Abstract
Aim: The purpose of the study was to examine the efficacy of treating osteoarthritis of the knee joint using stem cells. Patients and Methods: The study included 10 patients with second-degree arthrosis, who were operated on at the Department of Orthopedics, Clinical Hospital Center Osijek. Preoperative patients were treated with the standard radiological knee imaging and MRI. The graft obtained by liposuction was centrifuged and mixed with platelet rich plasma (PRP), and was then applied to the diseased joint. Three months after the procedure, patients were contacted by phone and the data obtained was statistically processed. Results: After 3 months of application of stem cells to the knee joint, a statistically significant improvement occurred if joint swelling is observed, the pain while standing, walking on a flat surface and walking up the stairs. Conclusions: Although our study was conducted on a small number of subjects and the time was relatively short, the patients showed a significant functional improvement in clinical troubles. A further research and follow-up are needed to provide the treatment guidelines for this method, using a longer follow-up, and more subjects.
Keywords
osteoarthritis; stem cell; treatment
Hrčak ID:
241522
URI
Publication date:
1.9.2020.
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