Original scientific paper

On the Metabolism of β-Methionine-Methyl-C14

D. Keglević-Brovet ; Tracer Laboratory, Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia
A. Kornhauser ; Tracer Laboratory, Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia
B. Ladešić ; Tracer Laboratory, Institute »Ruder Bošković « Zagreb, Croatia, Yugoslavia
S. Iskrić ; Tracer Laboratory, Institute »Ruder Bošković « Zagreb, Croatia, Yugoslavia

Abstract

B-Amino-y-methyl-C14-thiobutyric acid (B-methionine-methyl -C14) fed in a single dose to rats caused a negligible activity of the carbon dioxide expired. Most of the activity was found in the urine due to the unchanged compound administered, as well as to its oxydation product B - amino- y - methyl - C14 - sulfoxibutyric acid (B-methionine sulfoxide). Choline and creatinine isolated from the body tissues and creatinine isolated from the urine showed a low activity. It is assumed therefore that under such conditions only a small fraction of B -methionine transfers its methyl group to the methyl acceptors.

Keywords

Hrčak ID:

246487

URI

https://hrcak.srce.hr/246487

Publication date:

4.5.1957.

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