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Acta clinica Croatica, Vol. 59. No. Supplement 1, 2020.

Review article

https://doi.org/10.20471/acc.2020.59.s1.12

Surgical Treatment of Recurrent Metastatic Parathyroid Gland Carcinoma

Zaviša Čolović ; University of Split, Split University Hospital Center, Department of Otorhinolaryngology, Split, Croatia
Mladen Krnić ; University of Split, Split University Hospital Center, Department of Endocrinology, Split, Croatia
Zlatko Kljajić ; University of Split, Split University Hospital Center, Department of Otorhinolaryngology, Split, Croatia
Mirko Kontić ; University of Split, Split University Hospital Center, Department of Otorhinolaryngology, Split, Croatia
Nikola Kolja Poljak ; University of Split, Split University Hospital Center, Department of Otorhinolaryngology, Split, Croatia
Robert Tafra ; University of Split, Split University Hospital Center, Department of Otorhinolaryngology, Split, Croatia
Petar Ivanišević ; University of Split, Split University Hospital Center, Department of Otorhinolaryngology, Split, Croatia

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Abstract

We present the case of a 48-year-old male patient who underwent surgery
for a recurrent metastatic parathyroid gland carcinoma in the patient’s right paratracheal space of the
neck. The patient had undergone surgery for lower right parathyroid gland carcinoma 28 months
earlier. Results: The metastases were resected en bloc with an ipsilateral central neck dissection and
with the removal of the enlarged lower left parathyroid gland. After exploration of the remnant parathyroid
glands we noticed that lower left parathyroid gland was macroscopically enlarged so we decided
to remove it to prevent possible hypercalcemia in future and to also prevent possible recurrence
of cancer or development of a new primary, considering the identical embryological origin of the
lower parathyroid glands and possibility of synchronous, multiple tumors, which generally follow the
same embryological origin if they occur. The patient was also treated with radiation therapy after the
surgery. Conclusion: With the present surgical approach to recurrent metastatic parathyroid gland
carcinoma, we aimed to prevent the recurrence of cancer or development of new primary and prevent
or delay hypercalcemia in the future with all severe adverse metabolic states associated with high serum
calcium levels.

Keywords

recurrent metastatic parathyroid gland carcinoma; embryological origin; surgical treatment

Hrčak ID:

248277

URI

https://hrcak.srce.hr/248277

Publication date:

1.11.2020.

Article data in other languages: croatian

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