Professional paper

https://doi.org/10.20471/acc.2020.59.s1.17

Povezanost diabetes mellitusa tip 2, hipotiroeoze i karcinoma štitnjače

Željko Zubčić ; Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Anamarija Šestak ; Department of Otorhinolaryngology, Vukovar General Hospital, Vukovar, Croatia
Hrvoje Mihalj ; Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Željko Kotromanović ; Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Andrijana Včeva ; Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Tin Prpić ; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Matej Rezo ; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Stjepan Grga Milanković ; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Vjeran Bogović ; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Ivan Abičić ; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia

Abstract

Cilj ove studije je bio ispitati povezanost diabetes mellitusa tip 2 (T2DM), antidijabetičke terapije, hipotireoze i karcinoma
štitnjače. Analizirani su podaci od 320 pacijenata koji su operirani zbog sumnje na karcinom štitnjače. Dijagnoza karcinoma
štitnjače je potvrđena patohistološkom analizom kod 95 pacijenata. Nije nađena značajna razlika u prisutnosti dijagnoze
T2DM i hipotireoze u odnosu na prisutnost karcinoma štitnjače (p=0.13; p=0.85), kao niti u spolu ispitanika s T2DM i
hipotireozom s obzirom na tip karcinoma štitnjače (p=0.19; p=0.25). Pacijenti s T2DM (Odds ratio [OR] 1.89; 95% CI,
0.856–4.163) i pacijenti s hipotireozom (OR, 1.05; 95% CI, 0.530–2.164) su imali veću vjerojatnost od karcinoma štitnjače,
kao i ispitanici koji su imali obje dijagnoze u kombinaciji (p=0.37; OR, 2.39; 95% CI, 0.333–17.278), u odnosu na pacijente
koji nemaju te dijagnoze. Muškarci s T2DM (OR, 6.19; 95% CI, 1.180-32.513) su imali veću vjerojatnost od karcinoma
štitnjače od žena. Veću vjerojatnost od karcinoma štitnjače imali su pacijenti koji uzimaju peroralne antidijabetike (OR, 1.91;
95% CI, 0.804–4.512) u odnosu na one koji uzimaju inzulin. Prema rezultatima ove studije možemo zaključiti da postoji
povezanost T2DM, hipotireoze, peroralnih antidijabetika i karcinoma štitnjače.

Keywords

diabetes mellitus tip 2; hipotireoza; karcinom štitnjače

Hrčak ID:

248286

URI

https://hrcak.srce.hr/248286

Publication date:

1.11.2020.

Article data in other languages: english

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