Case report

https://doi.org/10.20471/acc.2020.59.s1.19

Effect of Methimasole Therapy on Thyroid Patohistology that may Mimic Thyroid Malignancy

Ante Punda ; University Hospital of Split, Nuclear medicine department, Split, Croatia
Ana Barić ; University Hospital of Split, Nuclear medicine department, Split, Croatia
Zaviša Čolović ; University Hospital of Split, ENT department, Split, Croatia
Mirko Kontić ; University Hospital of Split, ENT department, Split, Croatia
Hrvoje Punda ; University Hospital of Split, Radiology department, Split, Croatia
Valdi Pešutić Pisac ; University Hospital of Split, Department for pathology, Split, Croatia

Abstract

Diffuse toxic goiter, as the most common cause of hyperthyroidism, is usually
initially treated with thyrostatic drugs such as methimazole, followed by radioiodine therapy or surgery
which may be indicated as definitive treatment. Radioactive iodine therapy has a known association
with various histopathologic features including cytologic atypia, but herein we present a rare example
of morphological thyrocyte changes induced by long-term pharmacological treatment with
methimazole that mimicked thyroid malignancy in a pathohistological sample.

Keywords

hyperthyroidsm; thyrostatic drugs; thyroid neoplasms

Hrčak ID:

248293

URI

https://hrcak.srce.hr/248293

Publication date:

1.11.2020.

Article data in other languages: croatian

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