Short communication, Note

A Synthesis of DL-a-Amino-B-hydroxy-valeric Acid. (Hydroxynorvaline)

D. E. Sunko ; Department of Physiology and Department of Chemistry, Medical Faculty, University of Zagreb, Croatia, Yugoslavia
A. Kisić ; Department of Physiology and Department of Chemistry, Medical Faculty, University of Zagreb, Croatia, Yugoslavia

Abstract

By applying the method used by Pfister et al. for the synthesis of threonine we prepared DL-a-amino-B-hydroxy-valeric acid (hydroxynorvaline) starting from ethyl B-keto-valerate. This amino acid was prepared earlier by different methods by Osterberg , Abderhalden and Heyns , Botviillii.k et al, Euston et al., and by Izumiya. The melting points of hydorxynorvaline and of its N-benzoyl derivate indicate that the product obtained consists mainly of the threo-isomer.

Keywords

Hrčak ID:

249399

URI

https://hrcak.srce.hr/249399

Publication date:

1.5.1955.

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