Conference paper
AWAKE BRUXISM TREATED WITH PREGABALINE IN A PATIENT WITH GENERALIZED ANXIETY DISORDER
Juan Martin Tecco
; Adult Psychiatic Unit, Centre Hospitalier Universitaire et Psychiatrique de Mons-Borinage (CHUP-MB), Mons, Belgium
Simona Tecco
; Dental School, Vita-Salute San Raffaele University, I.R.C.C.S. San Taffaele Hospital, Milan, Italy
Abstract
Background: Bruxism is excessive teeth grinding or jaw clenching. Several symptoms are commonly associated with bruxism,
including hypersensitive teeth, aching jaw muscles, headaches, tooth wear, and damage to dental restorations. There are two
types of bruxism, awake bruxism and sleep bruxism. Awake bruxism is generally treated by dentists and maxilla-facial surgeons
through several treatment modalities such as, counselling about triggers, relaxation, occlusal splints and botulinum toxin type A
injections.
Methods: We will present the case of a 21-year-old woman presenting mood swings with a high level of anxiety and concentration
difficulties since childhood. She also complained of awake bruxism. Intelligence was evaluated using The Wechsler Adult
Intelligence Scale - Fourth Edition (WAIS-IV). Attention-deficit hyperactivity disorder (ADHD) was investigated through a neuropsychology
test.
Results: Intelligence evaluation showed normal intellectual function. Neuropsychology test showed a profile corresponding to
ADHD. Bupropion XR 300 mg was initiated for ADHD. Pregabalin was prescribed for general anxiety syndrome. The patient
reported a complete disappearance of awake bruxism at a daily dose of 375 mg, with no occlusal appliances. Following the improvement
of the anxiety symptoms, the attempt to reduce the dose twice leading to the recurrence of bruxism
Conclusions: A 21 years old female treated with 375 mg daily doses of pregabalin for generalized anxiety disorder experienced
a significant reduction of daytime bruxism. More studies are needed to determine whether pregabalin has a long term effect against awake bruxism.
Keywords
awake bruxism; pregabalin; ADHD; treatment
Hrčak ID:
262356
URI
Publication date:
24.3.2020.
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