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Psychiatria Danubina, Vol. 31 No. suppl 3, 2019.

Conference paper

MOBIUS SYNDROME AND OBSESSIVE COMPULSIVE DISORDER: A CASE REPORT

Denis Jacques ; Université Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium ;Institut de Recherche Santé et Société, IRSS, Brussels, Belgium
Michel Ossemann ; Université Catholique de Louvain, Neurologic Unit, CHU UcL Namur Godinne Hospital, Yvoir, Belgium ;Institute of Neuro Sciences, IoNS, Brussels Belgium
Jean-Marc Timmermans ; Université de Mons, Clinical Orthopedagogy Unit, Mons, Belgium
Nicolas Zdanowicz ; Université Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium ;Institut de Recherche Santé et Société, IRSS, Brussels, Belgium
Thomas Dubois ; Université Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium

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Abstract

Background: Mobius syndrome is characterized by a bilateral congenital paralysis of the facial and abducens nerves which
leaves the subject with an expressionless "mask-like" face.
Subjects and methods: Based on a literature review and a case discussion of an adult patient with Mobius syndrome and
obsessive-compulsive disorder, initially undiagnosed and confused with a psychotic disorder, we will discuss the influence of Mobius
syndrome in psychiatric evaluations.
Results: The lack of facial expressiveness and non-verbal emotional interactions may influence psychiatric evaluations and
result in misdiagnosis and the inappropriate prescribing of antipsychotics. In the case analysis, we also observed other associated
malformations such as renal atrophy, a bicuspid aortic valve and mitral valve prolapse.
Conclusion: We feel that educating the patient about the communicative consequences of impaired facial expressions and facial
interactions is a necessary prerequisite for any psychiatric or psychological evaluation in subjects with Mobius syndrome. We also
recommend using caution when prescribing antipsychotics in patients with Mobius syndrome given the motor side effects secondary
to a potentially pre-existing hypotonia.

Keywords

Mobius syndrome; OCD; renal atrophy; bicuspid aortic; mitral valve prolapse; BCT; delusions; drug induced dystonia

Hrčak ID:

264119

URI

https://hrcak.srce.hr/264119

Publication date:

4.9.2019.

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